Archived News:
Minimizing Nonspecific Cellular Binding of
Quantum Dots with Hydroxyl-Derivatized Surface
Coatings
Posted: Fri., March. 7, 2008
Quantum-dot (QD) nanocrystals are promising fluorescent
probes for multiplexed staining assays in biological
applications. However, nonspecific QD binding to cellular
membranes and proteins remains a limiting factor in
detection sensitivity and specificity. Here we report a new
class of hydroxyl (-OH)-coated QDs for minimizing
nonspecific cellular binding and for overcoming the bulky
size problems encountered with previous surface coatings.....More Info
Nanometer-scale mapping and single-molecule
detection with color-coded nanoparticle probes
Posted: Fri., Feb. 29, 2008
We report a method for single-molecule detection and biomolecular
structural mapping based on dual-color imaging and automated
colocalization of bioconjugated nanoparticle probes....More Info
Gold Nanoparticle Probes May Allow Earlier Cancer Detection
Posted: Thurs., Jan. 17, 2008
Using tiny gold particles embedded with dyes, researchers have shown that they can identify tumors under the skin of a living animal. These tools may allow doctors to detect and diagnose cancer earlier and less invasively....More Info
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